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Course Detail

BS3025 Nuclear Magnetic Resonance in Structural Biology
Aims to develop learner fundamental understanding and fluency in practical applications of Nuclear Magnetic Resonance methods to determine 3D structures of biomolecules. It includes a study of the dynamics and intermolecular interactions both in solutions and in biological solids such as amyloids or filaments. The course aims to provide an overview of the power of NMR in applications ranging from the atomic resolution structures of proteins and ligand interactions to detailed 3D visualizations of live organisms. Since contemporary research in Structural Biology is rarely limited to the use of a single experimental method, understanding the fundamentals of NMR as one of the most important tools and integration with other methods like TEM and X-Ray are essential for those who are going to specialize in any field of Structural Biology.
Analysis of NMR structures of proteins and nucleic acids, Nuclear spin dynamics and NMR observables, NMR data acquisition and resonance assignment of small compounds, Resonance assignment strategies in small ligands and large proteins, NMR Data Acquisition using Nonlinear Sampling methods for automatic spectral analysis, 3D structure reconstruction of proteins in solution, Protein ligand interactions by NMR, NMR data acquisition of proteins, Mid-semester Quiz and integration of NMR in solution part, Solid state NMR spectroscopy of proteins and nucleic acids, Backbone resonance assignment strategies and structure determination of proteins in solids, Solid state NMR data acquisition of a protein, Integration and preparation for exam.
Who Should Attend
Reasearchers working in academia and the local biotech industry

Eligibility Criteria
Diploma/Degree in Biological Sciences and equivalent with 2 years of related working experience.
Date(s): 11 Jan 2021 to 07 May 2021
Time: Refer to Class and Exam Schedules
Venue: SBS-TR+5
Closing Date of Registration: 30 Nov 2020
Course Fee Payable:(Inclusive of GST) Refer to the course fee table

E2I No
Academic Units (AU)
Number of AU: 3
Online Registration
Method of Payment
  1. Online Credit/Debit Card Payment (VISA and Mastercard only)
  2. Cash/Cheque/NETS payment at One-Stop@SAC (NTU Main Campus)
Withdrawal & Refund Policy

Once payment is made, applicant is committed to the completion of course. Course fee refunds will not be considered.

Terms and Conditions
  1. Course is subject to a minimum participation number before commencement.
  2. Course is subject to a first-come-first-serve basis.
  3. Registration is non-transferable.
  4. Student must meet all eligibility criteria for admission.
  5. Student is required to complete all assessments for each course.
  6. PaCE@NTU​ reserves the right to change or cancel any course or lecturer due to unforeseen circumstances.
  7. All details are correct at time of dissemination.
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